A new colorectal cancer vaccine showed positive results in phase 1 clinical trial to demonstrate that the approach is safe. The patients treated had no signs of serious adverse events and samples of their blood contained markers of immune activation —…
Novel Therapies Slow CKD Progression in Patients With Diabetes
Treatment options for patients with Chronic Kidney Disease (CKD) are limited and often determined by the etiology of the CKD. RAAS blockade (ACE inhibitors or angiotensin receptor blockers) has so far been the only therapeutic intervention which has been shown to…
A Tiny Cry for Help From Inside the Liver Could Lead to Better Treatment
But when something comes along that badly injures enough of those cells—such as a liver-damaging overdose of pain medicine—this vital work can come to a screeching halt. With few good treatment options available, more than 2,000 Americans die of Acute liver…
¿Qué factores relacionados con el estilo de vida y el medio ambiente pueden influir en la infertilidad en mujeres y hombres?
Research consistently shows that lifestyle factors—what you eat, how well you sleep, where you live, and other behaviors—have profound effects on health and disease, including fertility. A number of lifestyle factors affect fertility in women, in men, or in both. These…
Mechanism to Form Influenza A Virus Discovered
The influenza A virus is known to form new strains every year. These strains are the result of small variations occurring at the level of the genome, which cause the virus to become different and no longer recognized by the immune…
Tipos de ensayos clínicos
Clinical Trials, phases I-IV, and types of Randomized Trials. Clinical trials are research studies performed in people that are aimed at evaluating a medical, surgical, or behavioral intervention. They are the primary way that researchers find out if a new treatment, like…
Buenas Prácticas Clínicas
Abstract Good Clinical Practice (GCP) is an international ethical and scientific quality standard for the design, conduct, performance, monitoring, auditing, recording, analyses and reporting of clinical trials. It also serves to protect the rights, integrity, and confidentiality of trial subjects. It…
What’s in This Plant? The Best Automated System for Finding Potential Drugs
Researchers at the RIKEN Center for Sustainable Resource Science (CSRS) in Japan have developed a new computational mass-spectrometry system for identifying metabolomes—entire sets of metabolites for different living organisms. When the new method was tested on select tissues from 12 plants…
El medicamento para la enfermedad renal de Proteon Therapeutics suspende el ensayo de fase III
Proteon Therapeutics, based in Waltham, Mass., announced that its PATENCY-2 Phase III clinical trial of vonapanitase in chronic kidney disease (CKD) failed to meet its co-primary endpoints. Vonapanitase was being evaluated in patients with Kidney disease (CKD) undergoing the creation of a radiocephalic…
NIH study finds no evidence that calcium increases the risk of AMD
Calcium-rich foods include milk, yogurt, and cheese, as well as non-dairy sources such as kale, white beans, and sesame seeds. NEI Eating a calcium-rich diet or taking calcium supplements does not appear to increase the risk of age-related macular degeneration (AMD),…