The results from a pooled analysis of two Phase 3 Halaven (eribulin) trials are published in Breast Cancer Research and Treatment. Findings from the pooled analysis show that eribulin improves overall survival in women compared to control. This overall survival benefit…
Multiple Models Reveal New Genetic Links in Autism
With the help of mouse models, induced pluripotent stem cells (iPSCs), and the “tooth fairy,” researchers at the University of California, San Diego School of Medicine have implicated a new gene in idiopathic or non-syndromic autism. This groundbreaking Autism research sheds…
Researchers Discover Promising Strategy for Fighting HIV
Harvard Stem Cell Institute (HSCI) researchers at Massachusetts General (MGH) and Boston Children’s hospitals (BCH) for the first time have used a relatively new gene-editing technique to create what could prove to be an effective technique for blocking HIV from invading…
Shutting Down Energy to Brain Cancer
A multicenter team of researchers has identified an enzyme key to the survival and spread of glioblastoma cancer cells that is not present in healthy brain cells, making the enzyme therapy a promising target. “With this enzyme, we may have found…
Increased Dosing of Malaria Drug in Children May Lower Infection Risk
Piperaquine is a long-acting malaria drug that kills residual parasites and decreases the risk of reinfection. A study led by Uppsala University researcher Martin Bergstrand shows that increasing the dose used in children could potentially decrease the yearly incidence of malaria…
World-First Embryonic Stem Cell Trial for the Heart
The long-awaited trial comes after much preclinical cell work on more than 350 rats, 50 immunodeficient mice and 32 non-human primates. “After 20 years in the stem cell area and a daily practice of cardiac surgery, I am very cautiously optimistic,”…
Drug Combination Shows Promise As Powerful Breast Cancer Treatment
The uncontrolled growth of cancer cells arises from their ability to hijack the cell’s normal growth program and checkpoints. Usually, after therapy, a second cancer-signaling pathway will open after the primary one shuts down — creating an ingenious escape route for…
EBC 46 Human Trials Destroy Tumors
Scientists at QIMR Berghofer Medical Research Institute have used an experimental drug produced from the seeds of a rainforest plant to cure solid cancer tumors in preclinical trials. The study led by Dr. Glen Boyle at QIMR Berghofer’s Cancer Drug Mechanisms…
1000s of Ebola Vaccine Doses in Coming Months
Thousands of doses of experimental Ebola vaccines should be available in the coming months and could eventually be given to health care workers and other people at high risk of the deadly disease, according to the World Health Organization. No vaccine…