For the first time, it has been shown that many mutations in tumors–20 percent—are immunogenic, or able to rouse armies of T cells, post-vaccine. Also for the first time, it has been shown that most of those roused T cell armies…
Researchers Study Potential Blood Test for Prostate Cancer
Vanderbilt University researcher William Mitchell, M.D., Ph.D., and colleagues in Germany and Canada have demonstrated a method for detecting “cell-free” tumor DNA in the bloodstream. Mitchell believes the technique will be transformative in providing improved cancer diagnostics that can both predict…
Combo Treatment Benefits Women with Metastatic Breast Cancer
Results of a Phase 2, open-label, dose-confirmation study of eribulin in combination with capecitabine, suggests that this therapy is efficacious in women with metastatic breast cancer (overall response rate 42.9% and clinical benefit rate 57.1%), with a safety and tolerability profile…
New Cause of Child Brain Tumor Identified
Doctors and scientists from The University of Manchester have identified changes in a gene, which can increase the risk of developing brain tumors in children with a rare inherited condition called Gorlin syndrome. Gorlin syndrome causes an increased risk of developing…
HIV Drug Blocks Bone Metastases in Prostate Cancer
Although prostate cancer can be successfully treated in many men, when the disease develops bone metastases, it is eventually lethal. In a study published online in the journal Cancer Research, researchers show that the receptor CCR5, best known for its role…
Big Data to Make Big Difference in Childhood Cancer Treatment
University of Technology Sydney (UTS) research crunching vast amounts of data on childhood cancer to better tailor treatment is one step closer to assisting clinicians as the collaboration with the Kids Research Institute at The Children’s Hospital at Westmead celebrates 12…
New Ways to Drain Cancer’s identify by Researchers
Scientists at the University of Manchester have discovered a potential weakness in cancer’s ability to return or become resistant to treatment, by targeting the ‘fuel’ part of stem cells which allows tumors to grow. Cancer stem cells are particularly difficult to…
Shutting Down Energy to Brain Cancer
A multicenter team of researchers has identified an enzyme key to the survival and spread of glioblastoma cancer cells that is not present in healthy brain cells, making the enzyme therapy a promising target. “With this enzyme, we may have found…
Vivolux Cancer Drug Receives FDA Clearance for Clinical Study
Vivolux, a pharmaceutical company specialized in cancer treatment, announced that the FDA has granted clearance to proceed with VLX1570 Clinical Trial phase 1/2 for treatment against relapsed and/or refractory multiple myeloma. Researchers at Vivolux have discovered a novel cancer drug target…