Harvard University chemists have achieved what a new paper calls a “landmark in drug discovery” with the synthesis of halichondrin. Known to be a potent anti-cancer agent in mouse studies, and found naturally in sea sponges. The halichondrin class of molecule…
Chemists’ Breakthrough in Synthesis Advances a Potent Anti-cancer Agent
It’s a feat three decades in the making: Harvard University chemists have achieved what a new paper calls a “landmark in drug discovery” with the total synthesis of halichondrin. Known to be a potent anti-cancer drug therapy agent in mouse studies,…
Cancer-Fighting Antibody Emerges During Sclerosis Research
While studying the underpinnings of multiple sclerosis, investigators at Brigham and Women’s Hospital came across important clues for how to treat a very different disease: cancer. In a paper published in Science Immunology, a group of researchers led by neurologist Howard…
Affordable Personalized RNA Cancer Vaccine Works, Aided by CD4 T Cells
For the first time, it has been shown that many mutations in tumors–20 percent—are immunogenic, or able to rouse armies of T cells, post-vaccine. Also for the first time, it has been shown that most of those roused T cell armies…
Big Data to Make Big Difference in Childhood Cancer Treatment
University of Technology Sydney (UTS) research crunching vast amounts of data on childhood cancer to better tailor treatment is one step closer to assisting clinicians as the collaboration with the Kids Research Institute at The Children’s Hospital at Westmead celebrates 12…
Fertility Drugs Do Not Increase Breast Cancer Risk
Women who took clomiphene citrate (brand name Clomid) or gonadotropins as a part of fertility treatment did not experience an increased risk for breast cancer over 30 years of follow-up, compared with women who were not treated with these medications, according…