GAZETTE: Where are we with Alzheimer’s, medically and scientifically? TANZI: We’re a lot farther along now than we were even last year. Back in 1986, as a Harvard student in the graduate school, my doctoral study was to discover the first Alzheimer’s gene,…
Research Finds “Fuzzy Thinking” Effect in Depression, Biopolar Disorder is Real
People with depression or bipolar disorder often feel their thinking ability has gotten “fuzzy”, or less sharp than before their symptoms began. Now, researchers have shown in a very large study that effect is indeed real – and rooted in brain…
Los cambios en los telómeros predicen el cáncer
A distinct pattern in the changing length of blood telomeres, the protective end caps on our DNA strands, can predict cancer many years before actual diagnosis, according to a new study from Northwestern Medicine in collaboration with Harvard University. The pattern…
Potentially Reversible Driver of Aging Found
Using stem cells and gene editing, Salk Institute researchers have unearthed a major driver of aging research, from cancer to diabetes. That driver: loss of heterochromatin, which is potentially reversible as it is an epigenetic process that does not initially forge…
Posible relación entre los azúcares de la diabetes y las placas cerebrales del Alzheimer
Diabetes and Alzheimer’s could have a cause-and-effect connection, according to a study published this week. Elevated blood sugar levels caused increased levels of amyloid beta, a fundamental ingredient of brain plaques in Alzheimer’s brains, in mice analyzed by the team from…
El tratamiento contra la hepatitis C elimina el virus en el 93% de los pacientes en un ensayo financiado por BMS.
En la continua competencia por encontrar tratamientos eficaces contra la hepatitis C, Bristol-Myers Squibb está probando su propia combinación de medicamentos: daclatasvir, asunaprevir y beclabuvir. Una dosis de 12 semanas de la combinación experimental de tres medicamentos contra la hepatitis C eliminó el virus en el 93 %...
El tratamiento combinado contra el cáncer de próstata podría vencer a la enfermedad en su propio terreno: estudio preliminar
When prostate cancer advances to the point of spreading, the larger and more stubborn tumors develop cells that suppress the body’s immune response – and defeat doctors’ attempts to launch an attack on it, experts said. But through chemoimmunotherapy, a chemical…
Investigadores descubren cómo la aspirina combate el cáncer
Get today’s drug discovery & development headlines and news – Sign up now! Taking aspirin reduces a person’s risk of colorectal cancer, but the molecular mechanisms involved have remained unknown until a recent discovery by The Hormel Institute, affiliated with the…
Una vacuna contra el cáncer basada en ARN personalizada y asequible funciona, con la ayuda de las células T CD4.
Por primera vez, se ha demostrado que muchas mutaciones en los tumores (el 20 %) son inmunogénicas, es decir, capaces de activar ejércitos de células T tras la vacunación. También por primera vez, se ha demostrado que la mayoría de esos ejércitos de células T activados...
3 Ways Technology is Changing the Face of Drug Discovery & Development
While personalized medicine has been a goal for some time, there have been several obstacles. Although there has been an explosion in genomic data, the corresponding clinical utility for this data has been slow to be validated. Data from tissue images,…