Take a look at 25 years’ worth of drug sales, and some familiar names pop up: the megablockbuster cholesterol drug Lipitor, for one. But you’ll also find some drugs that aren’t the mass-market successes Lipitor was. Amgen’s staple anemia treatment Epogen,…
Osteoporosis Drug May Benefit Heart Health
The osteoporosis drug alendronate was linked with a reduced risk of cardiovascular death, heart attack, and stroke in a Journal of Bone and Mineral Research study of patients with hip fractures. The association was seen for up to 10 years after fracture. In…
Discovery of How HIV Hedges its Bets Opens the Door to New Therapies
A stem cell is one with infinite possibilities. So, for decades, scientists have puzzled over how the cell chooses to keep being a stem cell and continue dividing or specialize into a specific cell type, like a heart or brain cell….
X-ray Laser Inspects Alzheimer, Parkinson’s Biomolecules
A new experimental method permits the X-ray analysis of amyloids, a class of large, filamentous biomolecules that are an important hallmark of diseases such as Alzheimer’s and Parkinson’s. An international team of researchers headed by DESY scientists has used a powerful…
CAR-T Immunotherapy Eliminates Metastatic Colorectal Cancer in Mice
Immunotherapy has given patients and oncologists new options, which for some patients, has meant cures for diseases that had been untreatable. Colorectal cancer has a high mortality rate in advanced stages of the disease with few effective therapies. Researchers at the…
Stem Cell Technology Boosts 3D Printed Cartilage Repair
Novel stem cell technology developed at the Swinburne University of Technology will be used to grow the massive number of stem cells required for a new hand-held 3D printer that will enable surgeons to create patient-specific bone and cartilage. The technology,…
BMS, Janssen Collab to Advance Next-generation Therapy for Cardiovascular Diseases
Source: https://abm-website-assets.s3.amazonaws.com/dddmag.com/s3fs-public/styles/content_body_image/public/embedded_image/2018/04/shutterstock_619251317.jpg?itok=KTVbwSTk The Janssen Pharmaceutical Companies of Johnson & Johnson announced it has entered a new worldwide collaboration with Bristol-Myers Squibb Company on a program to develop and commercialize Factor XIa (FXIa) inhibitors, including BMS-986177, for the prevention and treatment of…
Lupus Treatment Generates Positive Results in Phase III Clinical Trial
New research indicates that belimumab, a monoclonal antibody therapy that targets a component of the immune system, provides considerable benefits to patients with systemic lupus erythematosus (SLE), a predominately female, chronic inflammatory disease that can affect virtually any organ. The Arthritis &…
Artificial Pancreas is a Safe and Effective Treatment for Type 1 Diabetes
Use of an artificial pancreas is associated with better control of blood sugar levels for people with type 1 diabetes compared with standard treatment, finds a review of the available evidence published by The BMJ today. The findings show that artificial pancreas…