In your body, blood stem cells produce approximately 10 billion new white blood cells, which are also known as immune cells, each day. Even more remarkably, if some of these blood stem cells fail to do their part, other blood stem…
Maintenance Chemotherapy Extends Life for Children With a Rare Cancer
A new chemotherapy strategy improves cure rates for children with rhabdomyosarcoma (a rare cancer of the muscle tissue) who are at high risk for cancer recurrence. In a randomized phase III clinical trial, adding six months of low-dose maintenance chemotherapy after…
ASCO: AstraZeneca pioneer Lynparza scores with Zytiga combo in prostate cancer
CHICAGO—At last year’s American Society of Clinical Oncology annual meeting, AstraZeneca posted Lynparza data that would eventually make it the first in its class to break into breast cancer. This time around, it’s trying to grab the same crown in prostate cancer….
Stem Cell-Based Phase I Trial to Repair Spinal Cord Injuries Produces Encouraging Results
Writing in the June 1 issue of Cell Stem Cell, researchers at the University of California San Diego School of Medicine report that a first-in-human phase I clinical trial in which neural stem cells were transplanted into participants with chronic spinal cord…
Nanoparticles Take on Brain Cancer
Glioblastoma multiforme, a type of brain tumor, is one of the most difficult-to-treat cancers. Only a handful of drugs are approved to treat glioblastoma, and the median life expectancy for patients diagnosed with the disease is less than 15 months. MIT…
Experimental Drug Eases Effects of Gluten for Celiac Patients on Gluten-Free Diet
An investigational new drug offers hope of relief for celiac disease patients who are inadvertently exposed to gluten while on a gluten-free diet. Findings of the first phase 2 study of a biologic immune modulator in celiac disease will be presented…
Diabetes Researchers Find Switch for Fatty Liver Disease
Duke researchers have identified a key fork in the road for the way the liver metabolism deals with carbohydrates, fats, and protein. They say it could be a promising new target for combating the pandemics of fatty liver disease and prediabetes….
FDA Approves Aimovig™ (erenumab-aooe), A Novel Treatment Developed Specifically For Migraine Prevention
Migraine is a Severe Neurologic Disease That Profoundly Impacts Millions of Patients in the United States. Aimovig is the First and Only FDA-Approved Treatment to Block the Calcitonin Gene-Related Peptide Receptor (CGRP-R), Which Plays an Important Role in Migraine. Aimovig was…
From old behemoth Lipitor to new king Humira: Best-selling U.S. drugs over 25 years
Take a look at 25 years’ worth of drug sales, and some familiar names pop up: the megablockbuster cholesterol drug Lipitor, for one. But you’ll also find some drugs that aren’t the mass-market successes Lipitor was. Amgen’s staple anemia treatment Epogen,…
Osteoporosis Drug May Benefit Heart Health
The osteoporosis drug alendronate was linked with a reduced risk of cardiovascular death, heart attack, and stroke in a Journal of Bone and Mineral Research study of patients with hip fractures. The association was seen for up to 10 years after fracture. In…