The study found that weekend sleep didn’t make up for the harmful effects of sleep deprivation on the body’s metabolism. A good night’s sleep is vital for your health. Sleep helps your brain work properly. A lack of adequate sleep over…
Scientists find a new approach that shows promise for treating cystic fibrosis
In people with cystic fibrosis, a protein that releases a key infection-fighting agent (red spheres), is missing or defective (brown ribbon). Amphotericin (white structure) can form channels to release bicarbonate, restoring the antibiotic properties of the airway surface liquid, which plays…
Sage Wins FDA Approval for ‘Game-Changing’ Postpartum Depression Treatment
Shares of SAGE Therapeutics are up more than 3 percent in premarket trading after the company snagged approval for its postpartum depression treatment Zulresso (brexanalone) Tuesday afternoon. With the green light from the U.S. Food and Drug Administration (FDA), Zulresso is the first and only medicine…
Chemical Probe can Regulate Signaling Pathway and Block Cell Invasion by Arboviruses
Cells in humans and other vertebrates, as well as invertebrates, have to signal pathways that play essential roles in embryo development, cell proliferation, and tissue structuring. Dysregulation in one of these signaling pathways, known as the beta-catenin-dependent Wnt signaling pathway, can…
Leading Scientists Call for a Moratorium on Specific Types of CRISPR Editing
In the wake of the scandal caused by a Chinese researcher’s use of CRISPR-Cas9 gene editing to alter the DNA of embryos for seven couples, leading scientists called for a moratorium on heritable genome editing. In November 2018, He Jiankui, a researcher in Shenzhen, China,…
Seawater Bacteria Provides Leads to Fight Melanoma
Malignant Melanoma can be a particularly dangerous form of cancer, and more therapeutic options are needed. Now, researchers report in ACS Medicinal Chemistry Letters that a bacteria from seawater has inspired promising leads for an entirely new way to treat the…
Neurodegenerative Diseases Identified Using Artificial Intelligence
Researchers have developed an artificial intelligence platform to detect a range of neurodegenerative disease in human brain tissue samples, including Alzheimer’s disease and chronic traumatic encephalopathy, according to a study conducted at the Icahn School of Medicine at Mount Sinai and…
Tackling Parkinson’s With Targeted Drug Discovery
The failures and lack of progress in the development of new treatments for neurodegenerative diseases, such as Alzheimer’s and Parkinson’s disease, are well documented. But, finally, for patients who are desperately awaiting treatment, things may be changing. Advances in our understanding…
Analyzing Metagenome Helps Understand the Role of Bacterial Species in Crohn’s Disease
Research Overview on the Gut Metagenome Research on gut metagenome of patients with Crohn’s disease elucidates how it influences the taxonomic and functional composition of intestinal microbiota. Among the most common changes are the decrease in the diversity of beneficial microbes…
Sporadic Alzheimer’s in a Dish
The new cell model of the most common form of Alzheimer’s points to molecular causes, drug target Harvard Medical School geneticists has created a new model-in-a-dish of sporadic Alzheimer’s disease, which accounts for more than 90 percent of Alzheimer’s cases and…