Our blogs explain health conditions and clinical research in a way that is easy to follow, so readers can feel more informed
ASCO: AstraZeneca pioneer Lynparza scores with Zytiga combo in prostate cancer
CHICAGO—At last year’s American Society of Clinical Oncology annual meeting, AstraZeneca posted Lynparza data that would eventually make it the first in its class to break into breast cancer. This time around, it’s trying to grab the same crown in prostate cancer....
Stem Cell-Based Phase I Trial to Repair Spinal Cord Injuries Produces Encouraging Results
Writing in the June 1 issue of Cell Stem Cell, researchers at the University of California San Diego School of Medicine report that a first-in-human phase I clinical trial in which neural stem cells were transplanted into participants with chronic spinal cord...
Nanoparticles Take on Brain Cancer
Glioblastoma multiforme, a type of brain tumor, is one of the most difficult-to-treat cancers. Only a handful of drugs are approved to treat glioblastoma, and the median life expectancy for patients diagnosed with the disease is less than 15 months. MIT...
Experimental Drug Eases Effects of Gluten for Celiac Patients on Gluten-Free Diet
An investigational new drug offers hope of relief for celiac disease patients who are inadvertently exposed to gluten while on a gluten-free diet. Findings of the first phase 2 study of a biologic immune modulator in celiac disease will be presented...
Diabetes Researchers Find Switch for Fatty Liver Disease
Duke researchers have identified a key fork in the road for the way the liver metabolism deals with carbohydrates, fats, and protein. They say it could be a promising new target for combating the pandemics of fatty liver disease and prediabetes....
FDA Approves Aimovig™ (erenumab-aooe), A Novel Treatment Developed Specifically For Migraine Prevention
Migraine is a Severe Neurologic Disease That Profoundly Impacts Millions of Patients in the United States. Aimovig is the First and Only FDA-Approved Treatment to Block the Calcitonin Gene-Related Peptide Receptor (CGRP-R), Which Plays an Important Role in Migraine. Aimovig was...
From old behemoth Lipitor to new king Humira: Best-selling U.S. drugs over 25 years
Take a look at 25 years’ worth of drug sales, and some familiar names pop up: the megablockbuster cholesterol drug Lipitor, for one. But you’ll also find some drugs that aren’t the mass-market successes Lipitor was. Amgen’s staple anemia treatment Epogen,...
Osteoporosis Drug May Benefit Heart Health
The osteoporosis drug alendronate was linked with a reduced risk of cardiovascular death, heart attack, and stroke in a Journal of Bone and Mineral Research study of patients with hip fractures. The association was seen for up to 10 years after fracture. In...
Discovery of How HIV Hedges its Bets Opens the Door to New Therapies
A stem cell is one with infinite possibilities. So, for decades, scientists have puzzled over how the cell chooses to keep being a stem cell and continue dividing or specialize into a specific cell type, like a heart or brain cell....
X-ray Laser Inspects Alzheimer, Parkinson’s Biomolecules
A new experimental method permits the X-ray analysis of amyloids, a class of large, filamentous biomolecules that are an important hallmark of diseases such as Alzheimer’s and Parkinson’s. An international team of researchers headed by DESY scientists has used a powerful...
CAR-T Immunotherapy Eliminates Metastatic Colorectal Cancer in Mice
Immunotherapy has given patients and oncologists new options, which for some patients, has meant cures for diseases that had been untreatable. Colorectal cancer has a high mortality rate in advanced stages of the disease with few effective therapies. Researchers at the...
Stem Cell Technology Boosts 3D Printed Cartilage Repair
Novel stem cell technology developed at the Swinburne University of Technology will be used to grow the massive number of stem cells required for a new hand-held 3D printer that will enable surgeons to create patient-specific bone and cartilage. The technology,...