Researchers have determined that two Phase 1 drugs (CX-4945 and JQ1) can work together to efficiently kill T-cell acute lymphoblastic leukemia cells while having minimal impact on normal blood cells, representing a significant advancement in T-Cell Leukemia Treatment. Although both drugs…
Link Discovery Points to Potential New Alzheimer’s Treatment
Researchers have found that the proteins that control the progression of Alzheimer’s are linked in a pathway, and that drugs targeting this pathway may be a way of treating the disease, which affects 40 million people worldwide. The findings are published…
New Mouse Model May Open Autism Treatment Avenues
The hallmark of an excellent researcher is an open mind. That flexibility and openness is what led Nina Schor, the William H. Eilinger Chair of Pediatrics at the University of Rochester, to follow a hunch about a brain receptor– resulting in…
Researchers Discover Way to Develop Fast-Acting Antidepressants
UT Southwestern Medical Center researchers have generated fresh insights that could aid in the development of rapid-acting antidepressants for treatment-resistant depression. The researchers found that by blocking NMDA receptors with the drug ketamine, they could elicit rapid antidepressant effects in patients…
Jamming a Protein Signal Forces Cancer Cells to Devour Themselves
Under stress from chemotherapy or radiation, some cancer cells dodge death by consuming a bit of themselves, allowing them to essentially sleep through treatment and later awaken as tougher, resistant disease. Interfering with a single cancer-promoting protein and its receptor can…