Our blogs explain health conditions and clinical research in a way that is easy to follow, so readers can feel more informed
Researchers Map Paths to Cancer Drug Resistance
A team of researchers led by Duke Cancer Institute has identified key events that prompt certain cancer cells to develop cancer drug resistance to otherwise lethal therapies. By mapping the specific steps that cells of melanoma, breast cancer, and a blood...
Drug Blocks Key Signal in Cancer Growth and Drug Resistance
An experimental cancer drug may block an important driver for the survival, growth and spread of cancer cells. The first clinical trial of an experimental drug, called pictilisib, found the safety profile to be manageable in cancer patients at doses that...
High Vancomycin Doses Fuel Risk of Kidney Damage in Children
Results of a small Johns Hopkins Children’s Center study show that hospitalized children given high-dose IV infusions of the antibiotic vancomycin to treat drug-resistant bacterial infections face an increased risk for kidney damage — an often reversible but sometimes serious complication....
Microcapsule Eliminates Toxic Punch of Experimental Anti-Cancer Drug
Johns Hopkins researchers have developed a sugar-based molecular microcapsule that eliminates the toxicity of an anticancer agent developed a decade ago at Johns Hopkins, called 3-bromopyruvate, or 3BrPA, in studies of mice with implants of human pancreatic cancer tissue. The encapsulated...
Combo Treatment Benefits Women with Metastatic Breast Cancer
Results of a Phase 2, open-label, dose-confirmation study of eribulin in combination with capecitabine, suggests that this therapy is efficacious in women with metastatic breast cancer (overall response rate 42.9% and clinical benefit rate 57.1%), with a safety and tolerability profile...
Study Shows Serotonin Can Increase Risk of Drug Addiction
A study by Sarah Bradbury, who graduates with a PhD in Psychology next week, shows that the development of drug addiction is related to brain levels of serotonin—a chemical created by the human body that is responsible for maintaining mood balance....
New Cause of Child Brain Tumor Identified
Doctors and scientists from The University of Manchester have identified changes in a gene, which can increase the risk of developing brain tumors in children with a rare inherited condition called Gorlin syndrome. Gorlin syndrome causes an increased risk of developing...
HIV Drug Blocks Bone Metastases in Prostate Cancer
Although prostate cancer can be successfully treated in many men, when the disease develops bone metastases, it is eventually lethal. In a study published online in the journal Cancer Research, researchers show that the receptor CCR5, best known for its role...
Big Data to Make Big Difference in Childhood Cancer Treatment
University of Technology Sydney (UTS) research crunching vast amounts of data on childhood cancer to better tailor treatment is one step closer to assisting clinicians as the collaboration with the Kids Research Institute at The Children’s Hospital at Westmead celebrates 12...
New Ways to Drain Cancer’s identify by Researchers
Scientists at the University of Manchester have discovered a potential weakness in cancer’s ability to return or become resistant to treatment, by targeting the ‘fuel’ part of stem cells which allows tumors to grow. Cancer stem cells are particularly difficult to...
Last Patient Dosed in Phase 2a Alzheimer’s Study
Neurotrope, Inc. announced that the last patient has been dosed in its Phase 2a clinical trial of Bryostatin-1 for the treatment of patients with Alzheimer’s disease (AD). The trial is being conducted under an Investigational New Drug (IND) application filed by...
Virus Discovery Could Impact HIV Drug Research
A research team led by Portland State University biology professor Ken Stedman has unlocked the structure of an unusual virus that lives in volcanic hot springs. The discovery could pave the way for better drugs to treat Human Immunodeficiency Virus (HIV),...