Researchers have determined that two Phase 1 drugs (CX-4945 and JQ1) can work together to efficiently kill T-cell acute lymphoblastic leukemia cells while having minimal impact on normal blood cells, representing a significant advancement in T-Cell Leukemia Treatment. Although both drugs…
Minority Inclusion in Clinical Trials: When Diversity Priorities Show
Beyond the critical need for securing more study volunteers across the board in clinical trials, a popular concern in all areas of clinical research is achieving inclusion in clinical trials and promoting diversity. Whether in medical journals, popular press, social media,…
Colombian Pharmaceutical Market to See Strong Four Year Growth
The pharmaceutical market in Colombia is set to rise from $5 billion in 2015 to $7.1 billion by 2020, registering a compound annual growth rate (CAGR) of 7.3%, according to research and consulting firm GlobalData. The company’s latest report states that this substantial…
Tiny Gold Nanoparticles Could Help Develop New Pancreatic Cancer Therapy
A diagnosis of pancreatic cancer is often a death sentence because chemotherapy and radiation have little impact on the disease. In the U.S. this year, some 53,000 new cases will be diagnosed, and 42,000 patients will die of the disease, according…
Folinic Acid Could Help Children With Autism Communicate Better
Prescription doses of folinic acid, which is a reduced form of a B vitamin known as folate, could help improve the language and communication skills of children with autism spectrum disorder (ASD). These are the preliminary findings from a placebo-controlled trial…
Neuroscientists Identify Two Neuron Populations That Encode Happy or Fearful Memories
Our emotional state is governed partly by a tiny brain structure known as the amygdala, which is responsible for processing positive emotions such as happiness, and negative ones such as fear and anxiety. A new study from MIT finds that these…
Cocoa Compound Linked to Some Cardiovascular Biomarker Improvements
To the tantalizing delight of chocolate lovers everywhere, a number of recent studies employing various methods have suggested that compounds in cocoa called flavanols could benefit cardiovascular health. Now a systematic review and meta-analysis of 19 randomized controlled trials (RCTs) of…
Researchers: It’s Time to Consider Propranolol as Anti-Cancer Drug
Propranolol, a beta-blocker commonly prescribed to treat irregular heart rates and other conditions, has significant anti-cancer properties, say researchers in a new clinical study published in ecancermedicalscience. The Repurposing Drugs in Oncology (ReDO) project, an international collaboration between the Anticancer Fund, Belgium,…
Scientists Identify Potent New Anti-Obesity, Anti-Diabetes Target
Scientists Identify Promising Anti-Obesity Target for Weight Loss and Diabetes It is no secret that losing weight is difficult. Each year brings a new popular diet, “guaranteed” to succeed, yet the explosion of obesity in the United States continues. Current anti-obesity…
UNC Lineberger researchers identify DNA repair enzyme as a potential brain cancer drug target
Rapidly dividing cells rely on an enzyme called Dicer to help them repair the DNA damage that occurs as they make mistakes in copying their genetic material over and over for new cells. UNC Lineberger Comprehensive Cancer Center researchers have built…