{"id":3511,"date":"2014-12-23T13:36:05","date_gmt":"2014-12-23T18:36:05","guid":{"rendered":"https:\/\/fomatmedical.com\/?p=3511"},"modified":"2026-04-28T20:46:34","modified_gmt":"2026-04-29T03:46:34","slug":"vancomycin-kidney-damage-in-children","status":"publish","type":"post","link":"https:\/\/fomatmedical.com\/es\/blogs-updates\/vancomycin-kidney-damage-in-children\/","title":{"rendered":"Las dosis altas de vancomicina aumentan el riesgo de da\u00f1o renal en los ni\u00f1os"},"content":{"rendered":"
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Vancomycin kidney damage in children is a documented and measurable risk. A study from Johns Hopkins Children’s Center found that hospitalized children receiving high dose IV vancomycin for drug resistant infections face a real risk of kidney injury \u2014 one that rises with every additional dose. The findings, published in the Annals of Pharmacotherapy<\/a>, call for more careful prescribing and faster development of safer alternatives.<\/p>\n

What Is Vancomycin and Why Are Doses Rising?<\/strong><\/h3>\n

Vancomycin is an antibiotic reserved for drug resistant bacterial infections that do not respond to standard treatment. It has been used safely for decades. However, the rise of MRSA and similar resistant bacteria prompted new dosing guidelines in 2009, calling for higher doses when a resistant infection is suspected.<\/p>\n

Those guidelines were written for adults. Many pediatric hospitals began applying the same high dose approach to children to ensure the drug reaches levels strong enough to eliminate resistant bacteria. The result has been a growing concern around vancomycin kidney damage in children receiving prolonged or high dose therapy.<\/p>\n

Vancomycin Kidney Damage in Children at High Doses<\/strong><\/h3>\n

Researchers analyzed records from 175 children treated with vancomycin at Johns Hopkins between 2009 and 2010. They found that 14% developed kidney damage during treatment.<\/p>\n

The risk followed a clear dose related pattern. Every 5 milligram per kilogram increase in daily dose raised the risk of vancomycin kidney damage in children by 16%. A 44 pound child receiving 1,600 milligrams per day carries a 16% higher risk than a child of the same size receiving 1,200 milligrams daily.<\/p>\n

Other factors that increased risk included:<\/p>\n